Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 123 |
Director, Strategic Account Lead - Upstate NY
Cambridge, Massachusetts
Overview The Strategic Account Lead (SAL) roleleads strategic engagement and contracting with target key accounts in order to drive growth, revenue, and joint value creation for Alnylam and the customer by enabling and optimizingaccess toAl...
8h
| Job Type | Full Time |
Sr. Scientist, Clinical Pharmacology
Cambridge, Massachusetts
Overview: The Sr. Scientist in Clinical Pharmacology position will support a rapidly expanding clinical portfolio of promising RNAi therapeutics. The candidate in this position should be well versed in PK and PD with strong ability to criti...
8h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: Analytical Development at Alnylam is seeking a highly motivated Senior Scientist with expertise in Bioassay including cell-based assays using different cell types and detection formats, qPCR, ELISA . This role involves performing ...
8h
| Job Type | Full Time |
Sr Director, Global Market Insights
Cambridge, Massachusetts
Overview: Alnylam is seeking a Senior Director to lead Global Market Research across the portfolio. This leader will define the vision for market insights, shape the research agenda, and elevate how insights inform strategy and decisions ac...
8h
| Job Type | Full Time |
Associate Director, Clinical Pharmacology
Cambridge, Massachusetts
Overview: The Associate Director in Clinical Pharmacology position will support a rapidly expanding clinical portfolio of promising RNAi therapeutics. The candidate in this position should be well versed in clinical pharmacology, PK and PD ...
8h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Research Informatics group is looking for a Software Engineer II to develop, maintain, and support web applications and tools utilized by Research, Early Development, and other groups within Alnylam. These tools directly suppor...
8h
| Job Type | Full Time |
Scientist, CNS Biology Research
Cambridge, Massachusetts
Overview We are seeking a motivated and knowledgeable Scientist to join our CNS Biology Research team. The ideal candidate will bring a strong scientific background in motor neuron diseases and a deep understanding of the underlying disease...
8h
| Job Type | Full Time |
Field Reimbursement Director - Northern California
Cambridge, Massachusetts
Overview: Reporting to the Field Reimbursement Director, Lead, the Field Reimbursement Director will optimize access to Alnylam products in his/her region by understanding and addressing reimbursement and patient access challenges. This pos...
8h
| Job Type | Full Time |
Senior Medical Director, Clinical Research - Hepatology
Cambridge, Massachusetts
Alnylam Pharmaceuticals is seeking an imaginative physician drug developer. This is an opportunity to provide clinical leadership in developing RNAi therapeutics in Alnylam's rapidly expanding portfolio, which spans the areas of rare geneti...
8h
| Job Type | Full Time |
Cambridge, Massachusetts
The Director, Health Informatics leads the strategy development and execution of health information technology (HIT) capabilities that enable Alnylam engagement with healthcare systems and providers. This role partners with U.S. health syst...
1d
| Job Type | Full Time |