Staff Research Associate II - Laboratory for Genomics Research

University of California - San Francisco
United States, California, San Francisco
Nov 15, 2024
Staff Research Associate II - Laboratory for Genomics Research Laboratory for Genomics Research Full Time 80613BR Job Summary The Laboratory for Genomics Research (LGR) is a collaborative effort between UCSF, UC Berkeley, and GSK. The LGR is focused on scaling up current and next-generation functional genomics platforms to better understand the genetic basis of diseases. The LGR strives to build advanced CRISPR-based genome editing and functional genomics platforms empowered by human genetics and computational biology to discover novel drug targets, expand our understanding of the human genome across various disease contexts, and deliver innovative tools to accelerate functional genomics research across academia and industry. Explore our research at http://www.lgr.bio/projects. Under supervision, the Staff Research Associate 2 will be working in the Laboratory for Genomics Research (LGR) which is a new functional genomics center in which scientists use CRISPR/Cas9-based functional genomics tools to decipher biological functions of genes, identifying new drug targets and developing new technologies that will advance discovery in both academia and industry. In this position, he/she will be an integral member of a research team that is developing and implementing the next generation of CRISPR screening tools in human cell models to investigate the underlying causes of human disease biology and identify potential drug targets. The responsibilities can include culturing and maintaining human cell culture lines, performing flow cytometry and microscopy, performing standard molecular biology techniques, implementing automation protocols, performing basic statistical calculations, and other duties as assigned. Alternatively, the responsibilities can include extensive molecular biology work to develop new methods of sequencing sample preparation and/or supporting enabling technologies including scRNA-seq, high content imaging, and robotic-enabled pooled and arrayed screening. Some time will be spent performing literature reviews and attending and presenting at lab meetings/journal club meetings. Multiple openings are available. The final salary and offer components are subject to additional approvals based on UC policy. Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement. The salary range for this position is $28.04 - $45.09 (Hourly Rate). To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html Department Description The Laboratory for Genomics Research (LGR) is a collaborative effort between UCSF, UC Berkeley, and GSK. The LGR is focused on scaling up current and next-generation functional genomics platforms to better understand the genetic basis of diseases. The LGR strives to build advanced CRISPR-based genome editing and functional genomics platforms empowered by human genetics and computational biology to discover novel drug targets, expand our understanding of the human genome across various disease contexts, and deliver innovative tools to accelerate functional genomics research across academia and industry. Explore our research at http://www.lgr.bio/projects. Required Qualifications BA/BS in a related science (preferably biology or chemistry) and one or more years of recent, directly related work experience, utilizing the techniques or methods required by the position; and/or equivalent experience/training. Practical knowledge of basic molecular biology techniques and cloning Sterile technique and mammalian cell culture skills Ability to effectively use/maintain laboratory instruments such as flow cytometry instrument and/or cell sorter Excellent verbal and written communication skills Ability to use internet as a resource for experimental tasks and literature searches Working knowledge of MS Office (Word, Excel, Powerpoint) Math skills required for everyday calculations Capability to learn/use basic statistical tools Preferred Qualifications Practical knowledge of CRISPR/Cas9 system Flow cytometry skills Experience with sophisticated human cell models including iPSC-derived cells or primary cells Experience with or interest in developing and implementing lab automation protocols Drug dose titration skills About UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells. Pride Values UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values. In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu Join us to find a rewarding career contributing to improving healthcare worldwide. Equal Employment Opportunity The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Organization Campus Job Code and Payroll Title 009617 SRA 2 NEX Job Category Research and Scientific Bargaining Unit University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX) Employee Class Career Percentage 100% Location San Francisco, CA Campus Mission Bay (SF) Work Style Fully On-Site Shift Days Shift Length 8 Hours Additional Shift Details Standard, M-F 9am-5pm, occasional weekend time may be required