Analytical Development Senior Research Associate

Job Description

General Summary:

The Analytical Development Senior Research Associate independently performs complex experimental procedures designed through collaboration with their supervisor. Works collaboratively with the analytical team providing technical support to achieve program goals within established timelines and demonstrates excellent documentation skills. Independently performs troubleshooting as needed. Reports experimental findings and results to the team in an organized and clear manner. Authors method documents, analytical protocols and reports. Contributes to lab organization and efficient lab functioning.

This individual will help advance transformative medicines treating the underlying cause of serious diseases by contributing to analytical activities for small molecule programs from preclinical through late stage development. Responsibilities include analytical support of process and formulation development activities, including purity and stability characterization of drug substance and drug product, as well as contributing scientifically to the resolution of broader drug development challenges in collaboration with other CMC functions. The ideal candidate will have knowledge of laboratory techniques commonly used in the analysis of pharmaceuticals such as HPLC, GC, and KF.

Key Duties and Responsibilities:

• Designs, executes, and interprets experiments within SOPs and regulations, with a high degree of reliability and independence
• Collates and interprets data systematically, and compiles results into conclusions or recommendations for discussions with manager
• Conducts experimental troubleshooting on a routine basis
• Maintains accurate laboratory notebooks with inclusion of reference to sources of raw data
• Prepares clearly defined protocols and written reports
• Participates in the preparation of presentations and may present experimental results and conclusions at internal department or Project Team research meetings
• Contributes collaboratively to team goals, providing technical support where needed

Knowledge and Skills:

• Understanding of HPLC, KF, GC, and other techniques commonly used for pharmaceutical analysis
• Proven technical prociency and demonstrated skill in designing, executing and interpreting experiments
• Uses own judgment to execute follow-up experiments, including troubleshooting
• Demonstrated understanding of analysis and interpretation of complex experimental data with prociency in problem solving and protocol renement
• Effective communicator (written and verbal)
• Emerging knowledge of regulatory guidance for analytical development
• Ability to create and support a productive laboratory environment

Education and Experience:

• Bachelor's degree (or equivalent degree) in Chemistry, Chemical Engineering, Pharmaceutical Chemistry, or related discipline and 4+ years of experience in analytical development program or other analytical support function, or
• Master's degree (or equivalent degree) in Chemistry, Chemical Engineering, Pharmaceutical Chemistry, or related discipline and 0-2 years of experience in analytical development program or other analytical support function
• Knowledge and hands on experience with analytical techniques used for characterization and release assays (LC, GC, KF)

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com