Pharmacology Research Scientist-(Immunology)

Job Description

General Summary:

The Pharmacology Research Scientist works witha high degree ofindependence and is adept at conceptually outliningin vivoandin vitroimmunologicalstudies to design, execute and interpretassays to study the action of compounds on disease biology.Completes work in a resourceful, self-sufcientmanner andis able todesign alternative approaches to achieve desired outcomes. Keeps current on thescienticliterature relevant toscienticmethodologyor eld(s) of technicalexpertise. This level captures both the Research organization's entry level for staff with a research doctoral degree (PhD) and the advanced experimental expert leading one or more critical laboratory functions withhighimpact on drug discovery projects.

Key Duties and Responsibilities:

• Design andconductelaborate, conceptually connected, multi-component immunological and pharmacological experiments
• Collateand interpret complex datasystematically andsynthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new researchactivities
• Exercises solid judgment to prioritize studies, considering feasibility and Projectimpact
• Performs advanced and/or complex experimentaltroubleshooting
• Scours relevant scientic literature and routinelyincorporatenew insights into researchactivities
• Identies, prioritizes and introduces relevant emerging technologies in eld ofexpertiseto advance the existing technology platforms and create/maintaina competitiveadvantage
• Explores the feasibility of applying new scientic principles/concepts or implements andvalidatesnovel experimental approaches and technologies to achieve projectgoals
• Independently prepares study presentations and presents experimental conclusions at internal Group/Department or Project Team researchmeetings
• Contributes signicantly to patent and/or publicationpreparation
• Performs other duties asassigned

Knowledge and Skills:

• Demonstrated ability todesign,executeand interpretcompleximmunological and pharmacologicalin vivoandin vitroexperiments, to measure the action of compounds in disease relevant contexts
• Expertisein the development and optimization of complexin vivomodels of inflammation or autoimmune diseases
• Advanced skills in immunological techniques, such as flow cytometry, immunophenotyping, and in vitro/ex vivo cellular assays, to characterize immune responses and compound efficacy.
• Proficiencyin a wide range ofin vivotechniques, including routes of administration, blood/tissue harvesting, and processing for cellular/molecular analyses of immune responses and target engagement in immune models
• A broad working knowledge of fundamentalimmunology andpharmacology principles
• Demonstrates astute understanding of own discipline and the relevant literature
• Maintainsa high levelof knowledge related to current developments in the scientic Projecteld
• Displaysprovenproductivity and experimental creativity, and effective dissemination ofideas
• Demonstrates effective, self-sufcient communication skills, especially in peer-directedpresentations
• Demonstrates awareness of other Project-related disciplines and an understanding of general concepts and some experimental detail within thoseareas

Education and Experience:

• Ph.D. Immunology, pharmacology or related disciplineand 0-3 years ofrelevant post-doctoral employmentexperience or,
• Master'sdegree and 3+years ofrelevant employmentexperience or,
• Bachelor'sdegree and 6+years ofrelevant employmentexperience

#LI-KM4

#LI-Onsite

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com