Under the direction of the Healey Center Administrative Manager, Research, the SENIOR FINANCIAL ANALYST position supports the Sean M Healey & AMG Center for ALS (Healey Center) / Neurological Clinical Research Institute (NCRI). We are a diverse group of researchers, clinicians, project managers, information technologists, and administrators at Massachusetts General Hospital, collaborating with global partners to develop novel therapies for individuals with Amyotrophic Lateral Sclerosis (ALS, also known as Lou Gehrig's disease). Among other programs, the Healey Center is implementing the HEALEY ALS Platform Trial, which is testing multiple promising experimental therapeutics with increased access for people with ALS. The Healey Center and the NCRI function as a Coordination Center of the HEALEY ALS Platform Trial and other clinical trials in ALS - managing funding from philanthropy, foundations, and industry and collaborating with numerous external vendors, subcontractors, and clinical study sites.
As a member of the highly collaborative NCRI Finance and Contracts team, the SENIOR FINANCIAL ANALYST will be responsible for the full life cycle of clinical study site budgeting, contracting, and payment process, primarily for the HEALEY ALS Platform Trial, and for other Healey Center programs, as needed. Currently, approximately 75 clinical study sites may be active at any given time and engaged under multiple task order contracts across the platform trial. Future expansion to the number of sites may be necessary.
POSITION REQUIREMENTS: Bachelor's Degree required, with preference for concentration in Economics, Business, Accounting or Finance. 3-5 years of experience in Research Administration, Clinical Trials contracting or a financial analysis/ accounting function.
- Superior MS Excel, Word and PowerPoint skills. Experience with WorkDay, Insight, OnCore and additional application systems a plus.
- Familiarity with clinical trial operations, sponsored project policies, and management for industry-funded clinical trials.
- Strong customer focus in collaboration with sites, sponsors, and external stakeholders
- Highly analytical thinking with demonstrated talent for identifying, improving, and streamlining complex work processes.
- Ability to work independently and as a member of team.
- Excellent written and verbal communication skills.
- Ability to operate effectively in a fast-paced constantly changing environment.
- Experience working within a medical organization and team environment is strongly desired.
SITE BUDGET DEVELOPMENT and IMPLEMENTATION
- Interpret complex clinical trial protocols and develop per participant fee budget grids, justifications, and payment terms for clinical trial site agreements.
- Work with the NCRI Systems Management Team to operationalize the site's Per Participant Fee (PPF) budget, providing the PPF payment schema to be programmed into the Electronic Data Capture (EDC) system.
- Assist in the development of new prime award budgeting for the Healey Platform trial by preparing site PPF, milestone, and invoiceable budgets and site cost estimates.
- Co-Lead the Platform Trial Site Budget Task Force meetings and ad hoc activities - maintaining membership and contact list; developing agendas, presentations, and materials for review and discussion with the task force members; documenting and distributing meeting minutes and action items.
- Ensure budgets and research billing terms are financially feasible and in compliance with MGB and NCRI policies and procedures.
- Develop standard budgeting tools, templates, and guidance on best practices for establishing multicenter clinical trials.
- Develop and present financial reports on site metrics.
SITE CONTRACTING
- Serve as primary point of contact (POC) for the Healey Center/NCRI research study teams on platform trial site contracting and site budget and payment terms.
- Liaise with external sites and Mass General Brigham contracting offices in the development, negotiation, and execution of new or amendments to site Master Clinical Trial Agreements, site Task Orders (TOs) for incoming and ongoing regimens.
- Lead and/or proactively participate in meetings to identify and resolve site issues and to report on the status of site contract execution.
- Draft contracts using a template, integrating the budget and scope of services, and developing payment terms.
- Negotiate budget and payment terms with sites within the parameters allowed by prime award budgets.
- Analyze budget impacts.
- With the assistance of MGB central office legal support, facilitate the negotiation of changes to legal terms.
- Develop and maintain a system to track and report on the status of contract execution.
- Communicate the status of budget negotiation with stakeholders, escalating any issues that could impact the budget or project timelines for study start-up.
- Maintain shared drive space dedicated to housing negotiation and fully executed agreements.
- Work with the study team to transfer fully-executed site contracts to the electronic Trial Master File.
- Facilitate execution and maintain files of confidentiality agreements (CDAs/NDAs) with new sites.
- Develop communications to sites regarding contractual and financial matters, including deadlines for final invoice submission, payments reconciliations, and other administrative closeout tasks.
SITE PAYMENTS
- Initiate, review, and submit milestone payments to sites via WorkDay
- Draft, review, and submit quarterly PPF payment invoices
- Run queries and reconcile site payments to ensure accurate accounting
- Serve as the primary POC for site invoices for reimbursement of invoiceable budget items
- Maintain a database of invoiceable budget items
- Review summaries of site payments to identify any issues and work to resolve them
- Distribute site payment summaries and reconciliations to sites as required
SITE SUPPORT
- Serve as the central point of contact for sites for questions related to budget and payment terms.
- Manage the central email billing address for all site-related inquiries
- Develop and maintain a log of site Q&A as it relates to budget and payment terms.
- Prepare and deliver in-person and virtual presentations for participating sites and investigators, including conference sessions, task order launches, and ad-hoc briefings as needed
The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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Massachusetts General Hospital
Nov 24, 2025