Bioinformatics Analyst

• Job Type: Officer of Administration
• Bargaining Unit:
• Regular/Temporary: Regular
• End Date if Temporary:
• Hours Per Week: 20
• Standard Work Schedule:
• Building:
• Salary Range: $42.55-$42.55

Position Summary

The Department of Systems Biology at Columbia University Irving Medical Center is seeking to hire a part-time Bioinformatics Analyst to work in Dr. Dennis Vitkup's lab.

The Bioinformatics Analyst will participate in analysis of large-scale genomic data in genetic studies of human conditions and diseases.

Responsibilities

• Participate in computational and statistical model development for predicting genetic effect of genomic variation.
• Participate in computational analysis of large-scale genomic data to identify risk variants and genes in human conditions and diseases, such as autism and neurodevelopmental disorders.
• Maintain and improve bioinformatics pipelines for genomic variants annotation.
• Maintenance of computational pipelines for analyzing bulk, single-cell, and spatial genomics data.
• Meet with Core users to assist with experimental design and computational analysis and the development of scientific manuscripts.
• Carry out standard/custom bioinformatics projects for Core users with standard tools for unsupervised clustering, differential expression, cell-type identification, chromatin state analysis, gene ontology/pathway enrichment, and data visualization.
• Carry out custom bioinformatics projects for Core users involving more sophisticated tools that may require adaptation to specific biological questions including inference of pseudotemporal trajectories, gene regulatory networks, and cell-cell interactions.
• Prepare computer code for reproducible analysis.
• Prepare figures and text for manuscripts and presentations.
• Develop or implement emerging computational methods for analyzing bulk and single-cell genomic data.
• Perform other duties as assigned.

Minimum Qualifications

Requires a bachelor's degree or equivalent in education and experience, plus three years of related experience

Preferred Qualifications

• Master's degree, or higher, in biomedical informatics or systems or related field
• At least one year of experience in projects with data science or machine learning as a core component
• Proficient in Python, git, Linux-based HPC, and modern data science frameworks

Other Requirements

• Programming: Fluency with at least one general-purpose programming language (e.g. C/C++, Ruby, Perl, Python) and one language for scientific computing (R, MATLAB, Python)
• Demonstrated experience in genomic data analysis
• Demonstrated experience in statistical analysis
• Strong written and verbal communication skills

Equal Opportunity Employer / Disability / Veteran

Columbia University is committed to the hiring of qualified local residents.