Stem Cell Research Lab Manager - 136958

The Department of Medicine (DOM) is the largest department within the UCSD School of Medicine and is responsible for fulfilling the teaching, research, and clinical missions of the University of California, San Diego School of Medicine. The department employs approximately 500 salaried faculty, 168 academic appointees, 331 residents, fellow and postdocs and 479 staff personnel.

The Stem Cell Research Lab Manager serves as the primary experimental authority and guide for the Buitrago-Delgado Laboratory at UCSD Department of Medicine and the Division of Regenerative Medicine. Makes instrumental contributions to both the development and execution of a myriad of complex research initiatives.

Stem Cell Research Lab Manager performs job duties including but not limited to: training, providing in-direct supervision, mentoring, and providing hands-on technical feedback to experimental trainees; ensuring high-quality training and reliable execution of experimental protocols; spearheading the strategic expansion of the experimental infrastructure, encompassing critical decisions regarding equipment acquisition and reagent sourcing, thereby laying a robust foundation for cutting-edge research; conducting experiments focused on spatial transcriptomics, with an aim to generate invaluable data that will lead to the creation of the first spatial transcriptomics atlas or early mammalian embryogenesis and understanding how cells make developmental decisions.

The Stem Cell Research Lab Manager will perform a variety of assays that apply molecular and cellular biology techniques including the design and synthesis of probe libraries, preparation of human and mouse tissue samples, performance of spatial transcriptomics assays, antibody coupling, virus preparation, cell and tissue culture, muse embryo extractions, tissue sample preparation. Additionally, collaborate with the specialists in data analysis, engage in writing papers (methods sections). collaborating with peer groups at UCSD for specialized techniques, particularly in processing tissue samples; ensuring that the Laboratory remains at the forefront of innovative research in stem cells and developmental biology; and performing other duties as assigned.

• Demonstrated proficiency in problem-solving and critical thinking abilities.

• Theoretical and practical knowledge in cellular and molecular biology, developmental biology, stem cell or related field, histology as typically attained trough a Bachelor's degree, or an equivalent combination ox laboratory experience. Ten (10) years of experience preferred.
  Excellent communication skills, both in written form and in presentations, enabling clear articulation of complex scientific concepts.

• Advanced knowledge of and direct experience with spatial transcriptomics assays.

• Demonstrated ability to efficiently work with light, fluorescence and confocal microscopy. Required

• Demonstrated ability to quickly learn and adapt to new experimental techniques and methodologies.

• Demonstrated proficiency computer skills using Word, Excel, Power Point. Solid skills in create and maintain databases, and ability to quickly learn new programs/applications with minimal direction.

• Exposure to roles that need quick adaptation to new experimental techniques and methodologies. Required

• Demonstrated history in roles requiring proficiency in problem-solving and critical thinking abilities.

• Excellent interpersonal skills, demonstrated ability to communicate orally and in writing. Posses skills of tact, poise, diplomacy, confidentiality and flexibility in a laboratory environment that interacts with a diverse group of research and technical personnel. Preferred

• Demonstrated experience of working in a team and mentoring trainees.

• Demonstrated experience with cell culture.

• Occasional evenings and weekends may be required.

• Must be willing to work with animals, lentivirus, human tissue, and standard hazardous laboratory compounds.

• Employment is subject to a criminal background check.