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Sr Computational Scientist

Myriad Genetics
United States, Utah, Salt Lake City
322 North 2200 West (Show on map)
Oct 06, 2025
Overview

The Sr Computational Scientist builds and maintains the underlying assays and analytical pipelines, working closely with molecular biologists and software engineers. Contributions include validating product updates, developing statistical analysis methods, and sharing methods in the form of simple re-usable software.

Responsibility
  1. Make critical contributions to awesome products in a cutting-edge clinical genomics laboratory.

  2. Use rigorous data science and modern software best practices to create efficient, reliable, and optimized bioinformatics pipelines.

  3. Lead project teams that build, validate, and future-proof new products and product features.

  4. Work closely with talent molecular biologists, software engineers, automation engineers, and data scientists.

  5. Characterize data resulting from novel molecular assays and guide molecular protocol development from a statistical perspective.

  6. Mentor junior scientists and research associates, guiding the overall path and success of key projects.

  7. Author posters and publications demonstrating the scientific prowess of our products and algorithms that power the products.

  8. Work with legal staff to secure intellectual property rights for inventions pertaining to our products.

  9. Communicate results to stakeholders across the organization.

Qualifications
  1. PhD in Computational Biology, Statistics, Molecular Biology, Genetics, Computer Science, Systems Biology, Biophysics, Physics, or a related discipline.

  2. 5+ years of experience developing methods to analyze large, noisy real-world data sets (in the context of molecular biology and/or human genetics, a plus).

  3. Experience leading multi-departmental projects and mentoring junior scientists and research associates.

  4. Experience developing custom analysis methods and algorithms and analysis pipelines.

  5. Experience working with CLIA-validated assays and authoring CLIA validation plans, Illumina Next Generation Sequencing (NGS), and other sequencing platforms.

  6. Strong computation skills, fluency in Python and a workflow definition language, and knowledge of software engineering best practices.

  7. Multiple peer-reviewed publications.

  8. Experience with modern medical genetics data sets preferred.

  9. Working knowledge of nucleic acid chemistry and genetics preferred.

  10. A sense of humility coupled with deep compassion, impeccable integrity, and an eagerness to be part of a caring and supportive team.

Physical Requirements

Lifting Requirements - light work or exerting up to 20 pounds of force frequently. Physical Requirements - stationary positioning, moving, operating, ascending/descending, communicating, observing, pushing or pulling, and reaching. Use of equipment and tools necessary to perform essential job functions.

EEO

We recognize that our people are our strength and the diverse talents they bring to our global workforce are directly linked to our success. We are an equal opportunity employer and place a high value on diversity and inclusion at our company. In hiring and all other employment decisions, we prohibit discrimination and harassment on the basis of any protected characteristic, including race, religion, color, national origin, gender, sexual orientation, gender identity, gender expression, age, marital or veteran status, pregnancy or disability, or any other basis protected under applicable law. In accordance with applicable law, we make reasonable accommodations for applicants' and employees' religious practices and beliefs, as well as any mental health or physical disability needs.

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