Molecular & Cell Biology Research Scientist, Tissue & Cell Characterization

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, California, San Diego
11010 Torreyana Road (Show on map)
Jun 03, 2025
Job Description Vertex is seeking a highly motivated scientist to join the Molecular and Cell Biology (MCB) group in San Diego. As part of the tissue and cell characterization function you will help evaluate and validate novel targets, characterize human donor tissues, uncover causal biology of new diseases, and drive the development of human disease-relevant models of serious genetic diseases. The ideal candidate will combine extensive hands-on experience with histology techniques and managing histology laboratory workflows with willingness to work hard and tenacity to solve problems and execute goals to help develop transformative medicines for people with serious diseases and significant unmet need. This is a full time, onsite position in San Diego. Knowledge and Skills: Management and maintenance of manual and automated histology lab equipment Tissue grossing, processing, and embedding Microtomy, cryosectioning - at volume (100+ samples/week) Histological staining: H&E and special stains IHC/ISH staining - manual and automated (Ventana, Leica Bond) Automated slide scanning (brightfield, fluorescence) Multiple imaging modalities including brightfield, fluorescence, SEM, and TEM Image Analysis (HALO, Visiopharm, custom scripting) Image data management Coordination and collaboration with other departments to facilitate lab functions, and develop efficient, safe, and robust histology lab workflow Exceptional organization skills and attention to detail for accurate sample processing and tracking Reliability and flexibility to work as needed for processing donor tissues outside of normal working hours including weekends and holidays Ability to work in a fast-paced environment, maintain timelines and adaptability to evolving priorities Tenacious problem solver, with initiative and drive to find resources and solutions Education and Experience: Ph.D. (or equivalent degree) in Biology, or related disciplines and 0-3+ years of relevant post-doctoral employment experience, Masters Degree (or equivalent degree) in Biology, or related disciplines and 3+ years of relevant employment experience, or Bachelors Degree (or equivalent degree) in molecular biology, cell biology, biochemistry, or related disciplines and 6+ years of relevant employment experience #LI-KM1 #LI-Onsite Pay Range: $118,500 - $177,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com