Make your mark for patients
We are seeking a Scientist II to join the US translational biology group based in Cambridge, MA and contribute to translational biology drug discovery efforts with an emphasis on muscle biology. The candidate will have a lab-based function with a responsibility of designing, characterizing and deploying stem cell/3D models and other cellular/biochemical assays to be utilized in early drug discovery for multiple therapeutic programs and target discovery efforts. Collaborate in a matrixed team of scientists responsible for identification and knowledge building across pathobiological pathways and patient populations including those in neuromuscular disease related to nucleotide repeat expansions, genetic mutations, mitochondrial dysfunction or inflammation.
Base Salary: $97,600 to $128,100
Responsibilities:
- Model Development: Design, characterize and validate primary cell or stem cell/3D models for therapeutic programs.
- Assay Execution: Conduct cell-based functional assays to characterize therapeutic hits or validate new targets that could require gene editing.
- Stem Cell Differentiation: Maintain and differentiate iPSCs into various cell types for translational assays.
- Translational Assays: Perform complex assays (2D to 3D models) to enhance understanding of neuromuscular disease biology.
- Team Collaboration: Collaborate with cross-functional teams to integrate translational biology insights into therapeutic programs or new target proposals.
- Data Management: Document, analyze, and present data to internal teams.
Requirements:
- PhD with 2+ years or MS Degree with 6+ years in biology, cellular biology, bioengineering or related field.
Competencies:
- Strong assay development and drug discovery knowledge
- Experience with mammalian cell culture, molecular and biochemical assays.
- Strong attention to detail, and enthusiasm for learning.
- Skeletal muscle biology is a plus
- Stem cell culture, gene editing and imaging experience is a plus
If you are interested to learn more about R&D within UCB, please find more information here R&D at UCB.
RANDATUCB
Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!
About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.
Why work with us?
At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.
UCB is an equal opportunity employer. All qualified applicants will receive equal consideration for employment without regard to race/ethnicity, color, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on US-Reasonable_Accommodation@ucb.com for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
UCB Inc.
Apr 16, 2025