Group Leader, Principal Scientist, Antibody Engineering

The Opportunity

We are seeking a talented Principal Scientist (Group Leader) to join the Department of Antibody Engineering in Genentech Research and Development (gRED), where we discover and engineer life-changing antibody drugs through pioneering science and technology. The successful candidate will lead a group to collaboratively develop bi/multi-specific antibodies by building new technologies and workflows to advance future internal antibody drug discovery programs and identify lead clinical candidates.

Primary responsibilities will focus on three areas.

• Engage with therapeutic areas to design and apply new antibody MOAs at the interface of biology and molecular engineering

• Leverage structure-based engineering and internal AI/ML capabilities to design novel molecule formats

• Serve as molecule or project team leader to direct therapeutic antibody lead selection, optimization, and engineering to develop best- or first-in-class antibody therapeutics

The individual should be passionate about developing creative and innovative protein-based technologies using skills in protein engineering, structural biology, biochemistry, or molecular biology. Exceptionally strong leadership and communications skills are essential for the position as the individual is expected to collaborate across Antibody Engineering to discover and advance next generation therapeutics.

Who You Are

• Ph.D. in a biological science plus post doc experience, including at least 4 years of recent protein engineering and/or antibody engineering in academia, biotechnology and/or pharma.

• Strong background in protein engineering, molecular biology techniques, and/or structural biology is required.

• Solid record of accomplishments and publications as evidence of scientific knowledge.

• Deep commitment to working as part of teams.

• Strong communication and leadership skills.

Preferred

• Experience with engineering bi- or multi-specific antibody/protein formats is preferred.

• Experience with structure-based protein analysis is a plus.

Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $143,200 to $265,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#LI-KC2

#gRED

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.